A Study on Reducing Risk Factors for Biological Degeneration Using Advanced Glycation End-Products Markers in Meditation Practitioners
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Abstract
The objective of this study was to examine the reduction of risk factors for biological degeneration in the human body, particularly among meditation practitioners, and to compare the effects of such risk reduction using Advanced Glycation End-Products (AGEs) markers before and after meditation practice. The research employed a quasi-experimental design. The sample group consisted of 27 senior monks (Sangha administrators) who participated in Vipassana meditation at the Young Buddhists Vipassana Center (Chaloem Phra Kiat Center 2), Pathum Thani Province. AGEs values were collected using the AGE Marker tool before and after a 15-day meditation program. Additionally, a questionnaire was used to gather information on participants’ health. Quantitative data were analyzed using means, standard deviations, and dependent t-tests to determine differences before and after the intervention. For the qualitative aspect, content analysis was conducted, and findings were presented descriptively.
The research findings revealed as follows: 1) Regarding objectives 1 and 2, risk factors for biological degeneration primarily arise from dietary habits based on personal preference and lack of physical exercise. These behaviors lead to excess sugar and degraded protein-derived nutrients, triggering chemical reactions that cause cells to become misshapen, stiffer, less elastic, and accelerate organ degeneration. This results in the formation of Advanced Glycation End-Products (AGEs). Meditation practitioners were able to reduce stress, anxiety, depression, and cognitive decline, as well as lower blood pressure. Additionally, walking meditation (Iriyāpatha-sappāya: suitable posture) provides beneficial physical activity, while mindful nutrition (Bhojana-sappāya: suitable food) contributes positively to overall health.
2) Regarding objective 3, the mean values of Advanced Glycation End-Products (AGEs) before and after meditation practice did not show a statistically significant change.
A body of knowledge obtained from this study indicates that Vipassana meditation can help reduce risk factors for biological degeneration; however, the practice duration should exceed 15 days to achieve optimal effects. Extended practice can cultivate a focused and purified mind, free from defilements, and stable in concentration. Additionally, it can improve blood pressure, pulse, cognitive function, quality of life, and reduce depressive symptoms.
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