The Effect of Knowledge Management Program of Food and Drug Consumption Behavior in Change on Glomerular Filtration Rate for Patients with Chronic Kidney Disease Stage 3-4 in Primary Care Setting
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Abstract
Background: Chronic kidney disease (CKD) is a growing public health problem in Thailand, largely driven by non-communicable diseases and aging populations. Poor dietary and medication behaviors contribute to disease progression, yet knowledge gaps persist among patients and caregivers. This study aims to evaluate the effectiveness of a knowledge management program on dietary and medication behaviors in improving kidney function among CKD stage 3-4 patients and their caregivers in a primary care setting.
Methods: This one-group pre-post interventional study was conducted at the Primary Care Cluster of Pathumthani Hospital from December 2023 to December 2024. A total of 322 patients with stage 3-4 CKD participated in educational interventions focused on high-sodium and high-sugar foods, non-steroidal anti-inflammatory drugs (NSAIDs), herbal medicines, and unregulated supplements. The program employed easy-to-remember, targeted knowledge and included educational sessions as well as quarterly glomerular filtration rate (GFR) assessments. The primary outcome was the change in estimated glomerular filtration rate (eGFR) over 12 months, which was analyzed using paired t-tests.
Results: Participants showed a statistically significant improvement in eGFR, with a mean increase of +2.154 ml/min/1.73m² at final follow-up (p = 0.004) and +3.943 ml/min/1.73m² at peak (p < 0.001). Subgroup analyses found no significant differences in outcomes based on age, comorbidities, or insurance type.
Conclusion: The knowledge management program demonstrated effectiveness in improving kidney function among patients with stage 3-4 CKD. These findings support the incorporation of regular, targeted educational interventions that feature concise, easily memorable content into primary care settings to facilitate the slowing of glomerular filtration rate.
Keywords: chronic kidney disease, knowledge management program, primary care setting
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