Quality of life among Diabetes Mellitus type 2 patients treated with Insulin versus Triple Oral Hypoglycemic Drugs at DM Clinic, Police General Hospital
Main Article Content
Abstract
Background and Objective: This study aimed to compare the quality of life of patients with type 2 diabetes who received insulin injections with those who received three oral hypoglycemic drugs and factors related to the quality of life of patients with type 2 diabetes, in the Diabetes Clinic, Police General Hospital
Design: Cross-sectional descriptive study
Methods: Data were collected at the Diabetes Clinic, Police General Hospital from September to December 2020, using a questionnaire that included information on demographic data, diabetes status, and the Diabetes-39 questionnaire (a lower score meant a better quality of life). Data were analyzed using descriptive statistics, unpaired t-tests, and multiple linear regression analysis.
Results: 126 participants were recruited. The findings were that participants who received insulin injections were more likely to have a worse quality of life than those who received the three oral hypoglycemic drugs in both total scores and all dimensions (total quality of life score 31.31 ± 19.33 and 22.27 ± 13.71 respectively, p < 0.05). The factor associated with the overall quality of life was the type of treatment (Three oral drugs group was associated with a better quality of life). Hemoglobin A1C level was related to the quality of life in many dimensions. Female had better quality of life in the sexual functioning dimension (Beta = -0.470, p < 0.001).
Conclusions: Insulin-injected patients had worse quality of life than patients using three oral hypoglycemic drugs. Healthcare workers should be aware of those associated factors in deciding an appropriate treatment plan to maximize the patient's quality of life.
Article Details

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
The content and information in articles published in the PCFM journal are solely the opinions and responsibilities of the authors. The journal's editorial board does not necessarily agree with or share any responsibility for them.
All articles, information, content, images, etc., published in the PCFM journal are the copyright of the PCFM journal. If any individual or organization wishes to reproduce, distribute, or use any part or the entirety of the content, they must obtain written permission from the PCFM journal beforehand.
References
World health organization. Diabetes [Internet]. 2020. [cited 2020 Jul 9]. Available from: https://www.who.int/health-topics/diabetes.
International Diabetes Federation. Diabetes in WP [Internet]. 2019. [cited 2020 Jul 9]. Available from:
https://www.idf.org/our-network/regions-mem-bers/western-pacific/diabetes-in-wp.html.
กองโรคไม่ติดต่อ กรมควบคุมโรค. ข้อมูลโรคไม่ติดต่อ [อินเทอร์เน็ต]. 2562. [เข้าถึงเมื่อ 9 กรกฎาคม 2563]. เข้าถึงได้จาก: http://www.thaincd.com/2016/mission/documents.php?tid=32&gid=1-020.
สำนักงานพัฒนานโยบายสุขภาพระหว่างประเทศ. รายงานภาระโรคและการบาดเจ็บของประชากรไทย พ.ศ. 2554. นนทบุรี: สำนักงานกิจการโรงพิมพ์สงเคราะห์องค์การทหาร ผ่านศึก; 2557.
สมาคมโรคเบาหวานแห่งประเทศไทย. แนวทางเวชปฏิบัติสำหรับโรคเบาหวาน. ปทุมธานี: ร่มเย็น มีเดีย; 2560.
WHO. WHOQOL: Measuring Quality of Life [Inter- net]. WHO. World Health Organization. [cited 2020 Jul 13]. Available from: https://www.who.int/healthinfo/survey/whoqol-qualityoflife/en/.
Boyer JG, Earp JAL. The development of an instru- ment for assessing the quality of life of people with diabetes: Diabetes-39. Med Care. 1997;35:440-53.
Songraksa K, Lerkiatbundit S. Development of a disease specific quality of life instrument: Thai version of the Diabetic-39. Songkla Med J. 2009;27:35-49.
Ananchaisarp T, Pringraksa S, Suaiyala J, Thet-asen N, Promvikorn S, Angsawat S, et al. Quality of life in diabetic patients in the primary care unit. J Health Sci Med Res. 2020;38:9-16.
Chaithong K, Namjaidee S, Phimarn W. Quality of life in diabetic outpatients at Pueainoi hospital, Khon Kean. J Sci Technol MSU. 2017;36:553-60.
Machin D, Campbell M, Tan S, Tan S. Sample size tables for clinical studies. 3rd ed. Chichester: WileyBlackwell; 2009.
พวงรัตน์ ทวีรัตน์. วิธีการวิจัยทางพฤติกรรมศาสตร์และสังคมศาสตร์. กรุงเทพฯ: สำนักทดสอบทางการศึกษาจิตวิทยา มหาวิทยาลัยศรีนครินทรวิโรฒประสานมิตร; 2540.
Dabrowski M, Filip W, Huc B. Association between insulin therapy and quality of life in diabetes. J PreClin Clin Res. 2017;11:10-4.
Abedini M, Bijari B, Miri Z, Emampour S, Abbasi A. The quality of life of the patients with diabetes type 2 using EQ-5D-5 L in Birjand. Health Qual Life Outcomes. 2020;18:18. doi: 10.1186/s12955-020-1277-8.
Harahap AW, Nasution MS. Comparison quality of life patients treated with insulin and oral hypogly- cemic drugs. Earth Environ Sci. 2018;125:1-6.
Hsu H-C, Lee Y-J, Wang R-H. Influencing pathways to quality of life and HbA1c in patients with diabetes: a longitudinal study that inform evidence-based practice. Worldviews Evid Based Nurs. 2018;15:104-12.
Al Hayek AA, Robert AA, Al Saeed A, Alzaid AA, Al Sabaan FS. Factors associated with health-related quality of life among saudi patients with type 2 dia- betes mellitus: a cross-sectional survey. Diabetes Metab J. 2014;38:220-9.
Changchuea W. Quality of life of diabetic patient in Sawaeng Ha district, Ang Thong province. Reg 4 Med J. 2013;15:97-104.
Visuthsiri W. Factors relating to the quality of life for: type ii diabetes mellitus patients at the 360 Degree Clinic, Vachira Phuket Hospital. Reg 11 Med J. 2015;29:33-42.
เสกสรร หีบแก้ว. คุณภาพชีวิตของผู้ป่วยโรคเบาหวานชนิด ที่ 2 อำเภอกุฉินารายณ์ จังหวัดกาฬสินธุ์. วิทยานิพนธ์ปริญญาสาธารณสุขศาสตรมหาบัณฑิต บัณฑิตวิทยาลัย มหาวิทยาลัยขอนแก่น; 2554.
Bąk E, Nowak - Kapusta Z, Dobrzyn-Matusiak D, Marcisz-Dyla E, Marcisz C, Krzemińska S. An assess- ment of diabetes-dependent quality of life (AD- DQoL) in women and men in Poland with type 1 and type 2 diabetes. Ann Agric Environ Med. 2019 Sep 19;26:429-38.
โสภิต อุบล. คุณภาพชีวิตของผู้ป่วยโรคเบาหวานชนิดที่ 2 ที่มารับบริการที่โรงพยาบาลถ้ำพรรณรา. วารสารสุขภาพประชาชนภาคใต้. 2557;28:18-24.
Srichaijaroonpong S, et al. Factors relating to the quality of life of the diabetic patients at Ban Chi- ang Kruea Pho Chai health promoting hospital, Chi- ang Kruea subdistrict, Muang district, Sakon Nakorn province. J Off DPC 7 Khon Kaen. 2016;23:23-33.
Safavi M, Samadi N, Mahmoodi M. Effect of quality of life improvement on type 2 diabetes patients’ self-esteem. Saudi Med J. 2011;32:797-801