Comparison of Relationships between Fasting blood glucose and Post-prandial blood glucose level with HbA1c level among Type 2 Diabetes mellitus Patients
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Abstract
Background: Some diabetes mellitus patients are not able to control the target Hemoglobin A1C levels even if their fasting plasma glucose level is good. This is partly caused by the postprandial plasma glucose that affects the Hemoglobin A1C levels, most of which are not properly assessed in practice.
Objective: To compare the relationship between the fasting blood glucose and two-hour postprandial blood glucose with HbA1c levels in type 2 diabetes mellitus patients.
Method: A cross-sectional descriptive correlation study in 84 type 2 diabetes mellitus patients were categorized into three groups as good diabetic control (HbA1c< 7%), moderate diabetic control (HbA1c = 7 to 8.4%) and poor diabetic control (HbA1c≥ 8.5%).
Result: Both fasting blood glucose and two-hour postprandial blood glucose levels were significantly correlated with HbA1c levels (r = 0.687 and 0.455, p< 0.001). Fasting blood glucose levels showed a better correlation to HbA1c levels than the two-hour postprandial blood glucose levels in a good diabetic control group (r = 0.588, p = .001). In a poor diabetic control group, fasting blood glucose and two-hour postprandial blood glucose levels were equally correlated with HbA1c levels (r = 0.672 and 0.654, p< 0.001). However, both tests were not significantly correlated with HbA1c levels in a moderate diabetic control group.
Conclusion: A two-hour postprandial blood glucose is an option for monitoring diabetic control in poorly controlled type 2 diabetic patients, especially in patients whose fasting blood glucose levels were good but HbA1c levels did not meet the target.
Keyword: Correlations, Type 2 Diabetes mellitus, HbA1c, fasting blood glucose, two-hour postprandial blood glucose
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