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This research paper aims to 1) study the conditions of science learning 2) study the factors which affect the science learning and skills development 3) offer guidelines for science learning and skills development. Quantitative research methods using a total of 205 schools, including 410 instruments to collect data from questionnaires and interviews. The findings were: 1. Operational conditions of teaching and learning science. A performance-based concept of the learning and teaching of science and 12 sectors of operational issues, such as current in all aspects of teaching and learning science, the format of the activities for learning, the role of school administrators ,the Learning Resources and the measurement and evaluation and others, respectively. 2. Factors that influence the skills development for teaching science has found that four factors: 1) The factor of teaching and learning of science, 2) factors of class 3) educational factors, and 4) variable factor is the skill of scientific thinking skills to solve problems. 3. Development of skills for teaching science that has been a key executive is must be promoted the science’s activities. Teachers should focus on the questions to encourage thought processes. Offer students the practical. To bring the attitude for science’s skill to the student can more focusing on the benefits of learning. Furthermore, the student must be applied the knowledge through analysis combining to create new applications that look different from the original.
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