Comparison of Quality of Life in Patients with Advanced Chronic Kidney Disease Undergoing Hemodialysis, Peritoneal Dialysis, and Comprehensive Conservative Management
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Abstract
Background: End-stage renal disease (ESRD) is a life-threatening condition that significantly impacts patients’ quality of life. While various treatment modalities are available, this research aims to investigate the quality of life among ESRD patients who receive Comprehensive Conservative Kidney Management (CCKM) compared to those undergoing renal replacement therapy (RRT).
Methods: A cross-sectional analytical study was conducted to compare the quality of life between CCKM (n=23) and RRT patients(n=69). The Thai version of KDQOL-SFTM was used as the assessment tool. Independent t-test and Mann-Whitney U-Test were performed for statistical analysis.
Results: The CCKM group had significantly higher mean age, proportion of low-income, and impaired physical function compared to the RRT group (p = 0.002, 0.006, and 0.002, respectively). No significant difference was found in kidney disease-specific quality of life between the two groups. The RRT group demonstrated significantly higher scores in overall general, physical health, and mental health-related quality of life compared to the CCKM group (p = 0.021, 0.012, and 0.025, respectively). However, after adjusting for confounding factors, there were no significant differences between the two groups in kidney disease-specific quality of life, overall generic quality of life, physical health-related quality of life, and mental health-related quality of life.
Conclusions: There were no significant differences in quality of life between the RRT and CCKM groups. Treatment modality selection for end-stage renal disease patients should consider the patient and family context individually.
Keywords: quality of life, kidney replacement, palliative, end-stage renal disease
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