Validation and Sensitivity /Specificity of Thai Knee Osteoarthritis Pre-Screening Questionnaire for Detection of Knee
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Abstract
Background: Knee osteoarthritis (OA) brings on a disability affecting the quality of life, mortality rates, and increasing cost of treatment. Screening for early diagnosis and risk assessment is a very useful secondary disease prevention. Thailand still has less knee OA screening and there is still no standard screening tool used in both adults and the elderly.
Objective: Evaluating validity and reliability involved sensitivity and specificity of the Thai version of the Knee Osteoarthritis Pre-Screening Questionnaire (KOPs) and estimating the prevalence of knee OA.
Methods: This diagnostic study had two phases. The first phase was translation and validation, the KOPs were translated into a Thai version then tested for content validity. Test-retest reliability was evaluated in 30 hospital staff. The second phase was diagnostic tool analysis and pilot study for prevalence in one hundred samples in the OPD.
Results: The Thai version of the KOPs questionnaire tested the content validity, in which the Index of Item – Objective Congruence (IOC) was greater than 0.5. From 30 hospital staff, the Thai version of the KOPS questionnaire yielded test-retest reliability of ≥ 80% and a Cronbach’s alpha of 0.804. The ROC curve revealed a sensitivity of 94.4% and specificity of 70.7% with a cut-off point at a score of 11.5. The prevalenceof knee OA according to the Thai KOPs questionnaire and ACR clinical/radiological diagnostic criteria was 34% and 18%, respectively.
Conclusions: Validated Thai version of the KOPs questionnaire is a quality tool for screening knee osteoarthritis for the Thai population, which can be used in the broader age group involving both adults and the elderly.
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