Association between diabetic retinopathy on sarcopenia and risk of falls in patients with type 2 diabetes
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Abstract
Objective: Diabetic retinopathy (DR) is a complication of type 2 diabetes mellitus (T2DM) that may lead to sarcopenia and risk of falls. This study aimed to investigate the association of DR with sarcopenia and the risk of falls.
Methods: We performed a cross-sectional analytical study by enrolling 265 T2DM patients 30 years and above who visited the Ophthalmic Outpatient Department, Trang Hospital from June-October of 2020. The tools used were divided into two parts: 1. Personal information 2. Physicalexamination, containing measuring muscle mass, handgrip strength, physical performance, and Time up and Go Test (TUG). The association between DR and other factors on sarcopenia and risk of falls was analyzed using multiple logistic regression.
Results: Of the patients with DR 22.4% had sarcopenia. The 53.7% DR patients had a risk of falls. No associations were found between DR and sarcopenia (adjusted OR = 0.09, 95% CI = 0-2.64, p = 0.161). DR was a protective factor of risk of falls (adjusted OR = 0.41, 95%CI = 0.18-0.91, p = 0.029). Being male was a risk factor of sarcopenia. The duration of T2DM, family history of T2DM, smoking, history of bone fracture, walking instability, glaucoma, diabetic nephropathy, waist circumference, systolic blood pressure, and osteoporosis were significant predictors of the risk of falls.
Conclusions: The presence of DR among patients with T2DM was not associated with sarcopenia but DR was a protective factor of risk of falls.
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