DRUG RELATED PROBLEM OF OUTPATIENTS RECEIVING WAFARIN WHO HAD THE INR OUT OF TARGET IN SATHINGPRA HOSPITAL

Abstract

This retrospective descriptive study aimed todetermine the prevalence and chrecteristics of drug related problems, adverse drug events and the severity of adverse drug eventsas well as pharmacists’ recommendations in outpatients receiving warfarin who had the INR out of target at the Warfarin Clinic of Sathingpra hospital. Patients’ information was collected from an electronic database and non-electronic database; patient counselling form. Data analysis was performed by descriptive statistics. Result of study showed that the INR out of target 230 times (58.38%), drug related problems were found in 191 times (83.04%). The third most frequent drug related problem was non-compliance (62.83%), warfarin-drug interaction (15.71%), and warfarin-food interaction (9.95%). Warfarin-related Adverse reaction were found in 5 times (1.26%); minor bleeding. Intervention to Physician by pharmacist about drug related problem occurred a total of 72 times and recommendations were accepted 62 times (86.11%). All recommendations associated with adverse drug reaction were accepted by physician (100%). In conclusion, the results of this study summarized important problem which will lead to improving further the pharmaceutical care process.