A Scoping Review of the Physical Health Needs of Family Caregivers of Older Women With Breast Cancer

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Mark Stephan Felix
Patreeya Kitcharoen
Thi Ngoc Phuc Le
Dewi Cahyani Puspitasari
Haihu Guo


This scoping review conducted mapping of relevant literature on the physical health needs of family caregivers of older women with breast cancer, gaps analysis, and suggests directions for future academic research. The PRISMA-ScR checklist by Tricco et al. (2018) guided the scoping review. Ten international databases were searched for academic articles published in English between January 2002 and January 2022. The 12,795 discovered articles were reduced to two sources of evidence. Extracted data were mapped out using a charting table. The analysis revealed a dearth of research on the subject of physical health of family caregivers of older women with breast cancer, a lack of detailed description of the physical health needs of family caregivers of older women with breast cancer, a lack of cultural, geographic, and ethnic diversity, a lack of studies on the physical needs/strains experienced by family caregivers aside from physical activity needs, underutilized research methodologies, gender differences that influence physical health needs of family caregivers, development of research tools, and lack of intervention/educational programs on physical health for family caregivers. Future research directions were suggested, and limitations were presented.

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Felix, M. S., Kitcharoen, P., Le, T. N. P. ., Puspitasari, D. C., & Guo, H. (2022). A Scoping Review of the Physical Health Needs of Family Caregivers of Older Women With Breast Cancer. Journal of Population and Social Studies [JPSS], 31, 216–234. Retrieved from https://so03.tci-thaijo.org/index.php/jpss/article/view/260665
Research Articles
Author Biography

Mark Stephan Felix, Department of Society and Health, Faculty of Social Sciences and Humanities, Mahidol University, Thailand

Corresponding author


• Advani, S., Abraham, L., Buist, D. S. M., Kerlikowske, K., Miglioretti, D. L., Sprague, B. L., Henderson, L. M., Onega, T., Schousboe, J. T., Demb, J., Zhang, D., Walter, L. C., Lee, C. I., Braithwaite, D., O’Meara, E. S., & Breast Cancer Surveillance Consortium. (2022). Breast biopsy patterns and findings among older women undergoing screening mammography: The role of age and comorbidity. Journal of Geriatric Oncology 13(2), 161–169. https://doi.org/10.1016/j.jgo.2021.11.013

• Ahles, T. A., Schofield, E., Li, Y., Ryan, E., Root, J. C., Patel, S. K., McNeal, K., Gaynor, A., Tan, H., Katheria, V., Vasquez, J., Traina, T., & Hurria, A. (2022). Relationship between cognitive functioning and frailty in older breast cancer survivors. Journal of Geriatric Oncology, 13(1), 27–32. https://doi.org/10.1016/j.jgo.2021.07.011

• Alatawi, Y., Hansen, R. A., Chou, C., Qian, J., Suppiramaniam, V., & Cao, G. (2021). The impact of cognitive impairment on survival and medication adherence among older women with breast cancer. Breast Cancer, 28(2), 277–288. https://doi.org/10.1007/s12282-020-01155-3

• Al-Rashdan, A., Xu, Y., Quan, M. L., Cao, J. Q., Cheung, W., Bouchard-Fortier, A., Kong., S., & Barbera, L. (2021). Higher-risk breast cancer in women aged 80 and older: Exploring the effect of treatment on survival. The Breast, 59, 203–210. https://doi.org/10.1016/j.breast.2021.07.005

• Bagayogo, F., Le Berre, M., Ruchon, C., Denis, J. L., Lamothe, L., Vedel, I., & Lapointe, L. (2020). Caring for older cancer patients: A scoping review. Health Policy, 124(9), 1008–1016. https://doi.org/10.1016/j.healthpol.2020.05.002

• Bovero, A., Vitiello, L. P., Botto, R., Gottardo, F., Cito, A., & Geminiani, G. C. (2022). Demoralization in end-of-life cancer patients’ family caregivers: A cross-sectional study. American Journal of Hospice and Palliative Medicine, 39(3), 332–339. https://doi.org/10.1177/10499091211023482

• Brick, R., Turner, R., Bender, C., Douglas, M., Eilers, R., Ferguson, R., Leland, N., Lyons, K. D., Toto, P., & Skidmore, E. (2022). Impact of non-pharmacological interventions on activity limitations and participation restrictions in older breast cancer survivors: A scoping review. Journal of Geriatric Oncology, 13(2), 132–142. https://doi.org/10.1016/j.jgo.2021.09.010

• Cao, W., Chen, H. D., Yu, Y. W., Li, N., & Chen, W. Q. (2021). Changing profiles of cancer burden worldwide and in China: A secondary analysis of the global cancer statistics 2020. Chinese Medical Journal, 134(7), 783–791. https://doi.org/10.1097/CM9.0000000000001474

• Celik, E., Aslan, M. S., Sengul Samanci, N., Karadag, M., Saglam, T., Cakan Celik, Y., Demerci, N. S., & Demirelli, F. H. (2022). The relationship between symptom severity and caregiver burden in cancer patients under palliative care: A cross-sectional study. Journal of Palliative Care, 37(1), 48–54. https://doi.org/10.1177/08258597211045780

• Chambers, A., Damone, E., Chen, Y. T., Nyrop, K., Deal, A., Muss, H., & Charlot, M. (2021). Social support and outcomes in older adults with lung cancer. Journal of Geriatric Oncology, 13(2), 214–219. https://doi.org/10.1016/j.jgo.2021.09.009

• Chávarri-Guerra, Y., Marcum, C. A., Hendricks, C. B., Wilbur, D., Cescon, T., Hake, C., Abugattas, J., Rodriquez, Y., Villareal-Garza, C., Yang, K., Cervantes, A., Sand, S., Castillo, D., Herzog, J., Mokhnatkin, J., Sedrak. M. S., Soto-Perez-deCelis, E., & Weitzel, J. N. (2021). Breast cancer associated pathogenic variants among women 61 years and older with triple negative breast cancer. Journal of Geriatric Oncology, 12(5), 749–751. https://doi.org/10.1016/j.jgo.2020.11.008

• Crouch, A., Champion, V. L., Unverzagt, F. W., Pressler, S. J., Huber, L., Moser, L. R., Cella, D., & Von Ah, D. (2022). Cognitive dysfunction prevalence and associated factors in older breast cancer survivors. Journal of Geriatric Oncology, 13(1), 33–39. https://doi.org/10.1016/j.jgo.2021.07.001

• de Boer, A. Z., Derks, M. G. M., de Glas, N. A., Bastiaannet, E., Liefers, G. J., Stiggelbout, A. M., van Dijk, M. A, Kroep, J. R., Ropela, A., van den Bos, F., & Portielje, J. E. A. (2020). Metastatic breast cancer in older patients: A longitudinal assessment of geriatric outcomes. Journal of Geriatric Oncology, 11(6), 969–975 https://doi.org/10.1016/j.jgo.2020.04.002

• Dijkman, B. L., Luttik, M. L., Van der Wal-Huisman, H., Paans, W., & van Leeuwen, B. L. (2022). Factors influencing family involvement in treatment decision-making for older patients with cancer: A scoping review. Journal of Geriatric Oncology, 13(4), 391–397. https://doi.org/10.1016/j.jgo.2021.11.003

• Farrington, N., Richardson, A., & Bridges, J. (2020). Interventions for older people having cancer treatment: A scoping review. Journal of Geriatric Oncology, 11(5), 769–783. https://doi.org/10.1016/j.jgo.2019.09.015

• Haynes-Maslow, L., Allicock, M., & Johnson, L.-S. (2016). Cancer support needs for African American breast cancer survivors and caregivers. Journal of Cancer Education, 31(1), 166–171. https://doi.org/10.1007/s13187-015-0832-1

• Hedenfalk, I., Duggan, D., Chen, Y., Radmacher, M., Bittner, M., Simon, R., Meltzer, P., Gusterson, B., Esteller, M., Raffeld, M., Yakhini, Z., Ben-Dor, A., Dougherty, E., Kononen, J., Bubendorf, L., Fehrle, W., Pittaluga, S., Gruvberger, S., Loman, N., ...Trent, J. (2001). Gene-expression profiles in hereditary breast cancer. New England Journal of Medicine, 344(8), 539–548. https://doi.org/10.1056/NEJM200102223440801

• Jansen, L., Dauphin, S., De Burghgraeve, T., Schoenmakers, B., Buntinx, F., & van den Akker, M. (2021). Caregiver burden: An increasing problem related to an aging cancer population. Journal of Health Psychology, 26(11), 1833–1849. https://doi.org/10.1177/1359105319893019

• Jauhari, Y., Gannon, M. R., Dodwell, D., Horgan, K., Clements, K., Medina, J., & Cromwell, D. A. (2021). Surgical decisions in older women with early breast cancer: Patient and disease factors. British Journal of Surgery, 108(2), 160–167. https://doi.org/10.1093/bjs/znaa042

• Karuturi, M. S., Giordano, S. H., Hoover, D. S., Volk, R. J., & Housten, A. J. (2022). Exploring and supporting older women's chemotherapy decision-making in early-stage breast cancer. Journal of Geriatric Oncology, 13(2), 170–¬175. https://doi.org/10.1016/j.jgo.2021.11.018

• Kowal, P. R., Peachey, K., & World Health Organization. (2001). Information needs for research, policy and action on ageing and elderly: A report of the follow-up meeting to the 2000 Harare MDS Workshop: Indicators for the minimum data set project on ageing: A critical review in sub-Saharan Africa, 21 and 22 June 2001, Dar es Salaam, United Republic of Tanzania. World Health Organization. https://apps.who.int/iris/handle/10665/69829

• Krietemeyer, M., Kemper, C., Clutter, J., & Krok-Schoen, J. L. (2022). The association of social support and income on the nutritional status and physical activity of older female cancer survivors. Journal of Geriatric Oncology, 13(3), 334–336. https://doi.org/10.1016/j.jgo.2021.11.005

• Krok-Schoen, J. L., Pennell, M. L., Saquib, N., Naughton, M., Zhang, X., Shadyab, A. H., Kroenke, C. H., Bea, J. W., Peterson, L. L., Crane, T., Wactawski-Wende, J., & Paskett, E. D. (2022). Correlates of physical activity among older breast cancer survivors: Findings from the Women's Health Initiative LILAC study. Journal of Geriatric Oncology, 13(2), 143–151. https://doi.org/10.1016/j.jgo.2021.11.012

• La, I. S., Johantgen, M., Storr, C. L., Zhu, S., Cagle, J. G., & Ross, A. (2021). Caregiver burden and related factors during active cancer treatment: A latent growth curve analysis. European Journal of Oncology Nursing, 52, Article 101962. https://doi.org/10.1016/j.ejon.2021.101962

• Lacaze, P., Bakshi, A., Orchard, S. G., Tiller, J. M., Neumann, J. T., Carr, P. R., Joshi, A. D., Cao, Y., Warner, E. T., Manning, A., Ngyuen-Dumont, T., Southey, M. C., Milne, R. L., Ford, L., Sebra, R., Schadt, E., Gately, L., Gibbs, P., Thompson, B. A., ... McNeil, J. J. (2021). Genomic risk prediction for breast cancer in older women. Cancers 13(14), Article 3533. https://doi.org/10.3390/cancers13143533

• Liu, X., Zheng, D., Wu, Y., Luo, C., Fan, Y., Zhong, X., & Zheng, H. (2021). Treatment patterns and outcomes in older women with early breast cancer: A population-based cohort study in China. BMC Cancer, 21(1), Article 226. https://doi.org/10.1186/s12885-021-07947-w

• Liu, Z., Heffernan, C., & Tan, J. (2020). Caregiver burden: A concept analysis. International Journal of Nursing Sciences, 7(4), 438–445. https://doi.org/10.1016/j.ijnss.2020.07.012

• Martin, C., Burton, M., & Wyld, L. (2022). Caregiver experiences of making treatment decisions for older women with breast cancer and dementia. Health and Social Care in the Community, 30(5), e2058–e2068. https://doi.org/10.1111/hsc.13640

• Morgan, J. L., Holmes, G., Ward, S., Martin, C., Burton, M., Walters, S. J., Cheung, K. L., Audisio, R. A., Reed, M. W. R., Wyld, L., & Bridging the Age Gap Trial Management Team. (2021). Observational cohort study to determine the degree and causes of variation in the rate of surgery or primary endocrine therapy in older women with operable breast cancer. European Journal of Surgical Oncology, 47(2), 261–268. https://doi.org/10.1016/j.ejso.2020.09.029

• Mosca, E., Alfieri, R., Merelli, I., Viti, F., Calabria, A., & Milanesi, L. (2010). A multilevel data integration resource for breast cancer study. BMC Systems Biology, 4(1), Article 76. https://doi.org/10.1186/1752-0509-4-76

• Onyeneho, C. A., & Ilesanmi, R. E. (2021). Burden of care and perceived psycho-social outcomes among family caregivers of patients living with cancer. Asia-Pacific Journal of Oncology Nursing, 8(3), 330–336. https://doi.org/10.4103/2347-5625.308678

• Orimo, H., Ito, H., Suzuki, T., Araki, A., Hosoi, T., & Sawabe, M. (2006). Reviewing the definition of “elderly.” Geriatrics & Gerontology International, 6(3), 149–158. https://doi.org/10.1111/j.1447-0594.2006.00341.x

• Overcash, J., Fugett, S., Tan, A., Ginther J., & Williams N. (2019). Strain among caregivers of older adults diagnosed with breast cancer. Oncology Nursing Forum 46(6), E185–E201. https://doi.org/10.1188/19.ONF.E185-E201

• Papadakos, J., Samoil, D., Umakanthan, B., Charow, R., Jones, J. M., Matthew, A., Nissim, R., Sayal, A., & Giuliani, M. E. (2022). What are we doing to support informal caregivers? A scoping review of caregiver education programs in cancer care. Patient Education and Counseling, 105(7), 1722–1730. https://doi.org/10.1016/j.pec.2021.10.012.

• Pedersini, R., di Mauro, P., Amoroso, V., Parati, M. C., Turla, A., Ghilardi, M., Vassalli, L., Ardine, M., Dalla Volta, A., Monteverdi, S., Borgonovo, K., Ghidhini, A., Cabiddu, M., Simoncini, E. L., Petrelli, F., Berruti, A., & Barni, S. (2020). Efficacy of Eribulin mesylate in older patients with breast cancer: A pooled analysis of clinical trial and real-world data. Journal of Geriatric Oncology, 11(6), 976–981. https://doi.org/10.1016/j.jgo.2020.03.021

• Pysklywec, A., Plante, M., Auger, C., Mortenson, W. B., Eales, J., Routhier, F., & Demers, L. (2020). The positive effects of caring for family carers of older adults: A scoping review. International Journal of Care and Caring, 4(3), 349–375. https://doi.org/10.1332/239788220X15925902138734

• Reblin, M., Donaldson, G., Ellington, L., Mooney, K., Caserta, M., & Lund, D. (2016). Spouse cancer caregivers’ burden and distress at entry to home hospice: The role of relationship quality. Journal of Social and Personal Relationships, 33(5), 666–686. https://doi.org/10.1177/0265407515588220

• Ren, L., Tian, X., He, Z., Song, E., & Tang, T. (2022). Cancer‐related fatigue in hospitalised patients treated for lymphoma and its burden on family caregivers. European Journal of Cancer Care, 31(1), Article e13547. https://doi.org/10.1111/ecc.13547

• Spatuzzi, R., Giulietti, M. V., Ricciuti, M., Merico, F., Romito, F., Reggiardo, G., Birgolotti, L., Fabbietti, P., Raucci., L., Rosati, G., Bilancia, D., & Vespa, A. (2020). Does family caregiver burden differ between elderly and younger caregivers in supporting dying patients with cancer? An Italian study. American Journal of Hospice and Palliative Medicine, 37(8), 576–581. https://doi.org/10.1177/1049909119890840

• Stjepanovic, N., Lubinski, J., Moller, P., Armel, S. R., Foulkes, W. D., Tung, N., Neuhausen, S. L., Kotsopoulos, J., Sun, P., Sun, S., Eisen, A., Narod, S. A., & Hereditary Breast Cancer Clinical Study Group. (2021). Breast cancer risk after age 60 among BRCA1 and BRCA2 mutation carriers. Breast Cancer Research and Treatment, 187, 515–523. https://doi.org/10.1007/s10549-020-06072-9

• Sun, V., Puts, M., Haase, K., Pilleron, S., Hannan, M., Sattar, S., & Strohschein, F. J. (2021). The role of family caregivers in the care of older adults with cancer. Seminars in Oncology Nursing, 37(6), Article 151232. https://doi.org/10.1016/j.soncn.2021.151232

• Sung, H., Ferlay, J., Siegel, R. L., Laversanne, M., Soerjomataram, I., Jemal, A., & Bray, F. (2021). Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: A Cancer Journal for Clinicians, 71(3), 209–249. https://doi.org/10.3322/caac.21660

• Thana, K., Sikorskii, A., Lehto, R., Given, C., & Wyatt, G. (2021). Burden and psychological symptoms among caregivers of patients with solid tumor cancers. European Journal of Oncology Nursing, 52, Article 101979. https://doi.org/10.1016/j.ejon.2021.101979

• Thomson, M. D., Genderson, M. W., & Siminoff, L. A. (2022). Understanding cancer caregiver burden over time: Dyadic assessments of family cohesion, conflict and communication. Patient Education and Counseling, 105(6), 1545–1551. https://doi.org/10.1016/j.pec.2021.10.014

• Tricco, A. C., Lillie, E., Zarin, W., O'Brien, K. K., Colquhoun, H., Levac, D., Moher, D., Peters, M. D. J., Horsley, T., Weeks, L., Hempel, S., Akl, E. A., Chang, C., McGowans, J., Stewart, L., Hartling, L., Aldcroft, A., Wilson, M. G., Garrity, C., ... Straus, S. E. (2018). PRISMA extension for scoping reviews (PRISMA-ScR): Checklist and explanation. Annals of Internal Medicine, 169(7), 467–473. https://doi.org/10.7326/M18-0850

• Unsar, S., Erol, O., & Ozdemir, O. (2021). Caregiving burden, depression, and anxiety in family caregivers of patients with cancer. European Journal of Oncology Nursing, 50, Article 101882. https://doi.org/10.1016/j.ejon.2020.101882

• Valachis, A., Nyström, P., Fredriksson, I., Wennstig, A.-K., & Ahlgren, J. (2021). Treatment patterns, risk for hospitalization and mortality in older patients with triple negative breast cancer. Journal of Geriatric Oncology, 12(2), 212–218. https://doi.org/10.1016/j.jgo.2020.09.004

• van der Plas-Krijgsman, W. G., de Boer, A. Z., de Jong, P., Bastiaannet, E., van den Bos, F., Mooijaart, S. P., Lifers, G. J., Portielje, J. E. A., & de Glas, N. A. (2021). Predicting disease-related and patient-reported outcomes in older patients with breast cancer - a systematic review. Journal of Geriatric Oncology, 12(5), 696–704. https://doi.org/10.1016/j.jgo.2021.01.008

• Verma, R., Saldanha, C., Ellis, U., Sattar, S., & Haase, K. R. (2022). eHealth literacy among older adults living with cancer and their caregivers: A scoping review. Journal of Geriatric Oncology, 13(5), 555–562. https://doi.org/10.1016/j.jgo.2021.11.008

• Yan, C. H., Coleman, C., Nabulsi, N. A., Chiu, B. C. H., Ko, N. Y., Hoskins, K., & Calip, G. S. (2021). Associations between frailty and cancer-specific mortality among older women with breast cancer. Breast Cancer Research and Treatment, 189(3), 769–779 https://doi.org/10.1007/s10549-021-06323-3

• Yu, W., Chen, J., Sun, S., Liu, P., Ouyang, L., & Hu, J. (2021). The reciprocal associations between caregiver burden, and mental health in primary caregivers of cancer patients: A longitudinal study: Family functioning, caregiver burden, and mental health. Psycho‐Oncology, 30(6), 892–900. https://doi.org/10.1002/pon.5667

• Zhang, X., Pennell, M. L., Bernardo, B. M., Clark, J., Krok-Schoen, J. L., Focht, B. C., Crane, T. E., Shaydyab, A. H., & Paskett, E. D. (2021). Body image, physical activity and psychological health in older female cancer survivors. Journal of Geriatric Oncology, 12(7), 1059–1067. https://doi.org/10.1016/j.jgo.2021.04.007